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In General Guidelines for Methodologies on Research and Evaluation of Traditional Medicine, published in 2000 by the World Health Organization (WHO), complementary and alternative medicine were defined as a broad set of health care practices that are not part of that country's own tradition and are not integrated into the dominant health care system.The expression also refers to a diverse range of related and unrelated products, practices, and theories ranging from biologically plausible practices and products and practices with some evidence, to practices and theories that are directly contradicted by basic science or clear evidence, and products that have been conclusively proven to be ineffective or even toxic and harmful.Almost none show any effect beyond that of false treatment, and most studies showing any effect have been statistical flukes.Alternative medicine is a highly profitable industry, with a strong lobby.

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Unlike medicine, an alternative product or practice does not originate from using scientific methods, but may instead be based on hearsay, religion, tradition, superstition, belief in supernatural energies, pseudoscience, errors in reasoning, propaganda, fraud, or other unscientific sources.Alternative therapies may even be allowed to promote use when there is demonstrably no effect, only a tradition of use.Regulation and licensing of alternative medicine and health care providers varies between and within countries.Alternative treatment is not the same as experimental treatment or traditional medicine, although both can be misused in ways that are alternative.Alternative or complementary medicine is dangerous because it may discourage people from getting the best possible treatment, and may lead to a false understanding of the body and of science.

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