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The project was significantly supported by the German Cancer Consortium (DKTK), the German Cancer Aid, the German Childhood Cancer Foundation, and the Federal Ministry of Education and Research (BMBF). Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort. Online publication 10th May 2018; DOI: A picture is available for download:https://de/de/presse/pressemitteilungen/2014/bilder/Picture Caption: MRT picture of a medulloblastoma Note on use of images related to press releases Use is free of charge.The German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) permits one-time use in the context of reporting about the topic covered in the press release.However, there are no standards for routine genetic screening of patients, nor are there guidelines and a corresponding nationwide infrastructure for genetic counseling of affected families.Scientists have now been able to characterize medulloblastoma more accurately and to derive recommendations for genetic testing based on analysis of 1022 patients with medulloblastoma."Mutations of this kind often indicate a familial predisposition to cancer and therefore place special demands on the treatment of patients and the counseling of families", said Paul Northcott from the St.Jude Children's Research Hospital in Memphis, who shares the lead authorship.The staff of the Cancer Information Service (KID) offers information about the widespread disease of cancer for patients, their families, and the general public.

The "Hopp Children's Cancer Center at the NCT Heidelberg" (Ki TZ) is a joint initiative of Heidelberg University Hospital and the German Cancer Research Center (DKFZ). Hopp Children's Cancer Center at the NCT Heidelberg" (Ki TZ)The Hopp Children's Cancer Center at the NCT Heidelberg" (Ki TZ) is a joint institution of the Heidelberg University Hospital and the German Cancer Research Center (DKFZ).As a therapy and research center for oncologic and hematologic diseases in children and adolescents, the Ki TZ is committed to scientifically exploring the biology of childhood cancer and to closely linking promising research approaches with patient care from diagnosis to treatment and aftercare.The results are particularly important because both, materials from previous studies and patient data from four current or recently completed clinical trials were included in the analysis.Based on these findings and other tumor features, the scientists developed criteria for routine genetic screening.

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