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Differentiation is related to the switching on of genes that were not operating previously.

Organs increase in size via cellular hypertrophy and hyperplasia.

During embryonal and fetal development, the fertilized oocyte changes into a complete organism representing the species by which the oocyte was produced.

In contrast, cells that undergo terminal differentiation divide only during a certain period of life of an individual.Jirásek's comparative classification (J' staging) is based only on external developmental characteristics of quadrupled vertebrate embryos.This classification is simple and suitable for the staging of a large number of animals.Differentiation is accomplished by formation of new structures (morphologic differentiation) and by formation of new chemical compounds (chemical differentiation).Development is (related to biological systems) a process resulting from a selective, time-related switching on and off of genes. The cell is a system of membranes, filaments and large molecules which prevent dissolved substances from mixing freely. In different biological systems, growth and differentiation are closely related.

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